Son muchisimas las frases q me hicieron llorar de la risa... pero sin duda la mejor es esta:

Penny: I'm a Sagittarius which probably tells you way more than you need to know...
Sheldon: Yes... it tells us that you participate in the mass cultural delusion that the sun's apparent position relevant to arbitrarily defined constellations at the time of your birth somehow affects your personality.
Penny: Participate in the what?